Table 1.
Sociodemographics in unvaccinated and vaccinated patients
| Characteristic | COVID vaccination during pregnancy |
Total (N=2002) | P valuea | |
|---|---|---|---|---|
| No (n=1862) | Yes (n=140) | |||
| Maternal age at delivery (y) | 30.5 (5.2) | 31.8 (3.7) | 30.1 (5.2) | <.001 |
| Race | .019 | |||
| Asian | 89 (4.8) | 6 (4.3) | 95 (4.8) | |
| Black or African American | 99 (5.4) | 3 (2.2) | 102 (5.1) | |
| Others combined | 128 (6.9) | 2 (1.4) | 130 (6.6) | |
| White | 1528 (82.9) | 128 (92.1) | 1656 (83.5) | |
| Unknown or not disclosed | 18 | 1 | 19 | |
| Ethnicity | .022 | |||
| Hispanic or Latino | 173 (9.5) | 5 (3.6) | 178 (9.1) | |
| Not Hispanic or Latino | 1651 (90.5) | 132 (96.4) | 1783 (90.9) | |
| Unknown or not disclosed | 38 | 3 | 41 | |
| Education (y) | <.001 | |||
| <12 | 70 (4.7) | 0 (0.0) | 70 (4.3) | |
| 12–16 | 1218 (81.9) | 70 (53.4) | 1288 (79.6) | |
| >16 | 199 (13.4) | 61 (46.6) | 260 (16.1) | |
| Not documented | 375 | 9 | 384 | |
| Current smoker | 196 (10.5) | 0 (0.0) | 196 (9.8) | <.001 |
| Illicit drug use | 56 (3.0) | 0 (0.0) | 56 (2.8) | .030 |
| Gravidity | .007 | |||
| 1 | 546 (29.3) | 56 (40.0) | 602 (30.1) | |
| 2 | 519 (27.9) | 34 (24.3) | 553 (27.6) | |
| 3 | 350 (18.8) | 29 (20.7) | 379 (18.9) | |
| ≥4 | 447 (24.0) | 21 (15.0) | 468 (23.4) | |
| Prepregnancy BMI | .004 | |||
| <25 | 573 (39.6) | 70 (56.5) | 643 (41.0) | |
| 25–30 | 409 (28.3) | 21 (16.9) | 430 (27.4) | |
| 30–35 | 226 (15.6) | 15 (12.1) | 241 (15.4) | |
| 35–40 | 139 (9.6) | 14 (11.3) | 153 (9.7) | |
| ≥40 | 99 (6.8) | 4 (3.2) | 103 (6.6) | |
| Not documented | 416 | 16 | 432 | |
| Pregestational diabetes mellitus | 11 (0.6) | 2 (1.4) | 13 (0.6) | .23 |
| Pregestational hypertension | 64 (3.4) | 6 (4.3) | 70 (3.5) | .63 |
| Asthma | 206 (11.1) | 15 (10.7) | 221 (11.0) | .90 |
| Infertility treatment | 14 (0.8) | 6 (4.3) | 20 (1.0) | .002 |
| Multiple gestation | .68 | |||
| Singleton | 1840 (98.8) | 138 (98.6) | 1978 (98.8) | |
| Twins | 22 (1.2) | 2 (1.4) | 24 (1.2) | |
| GBS test result | .51 | |||
| Negative | 1283 (80.8) | 94 (78.3) | 1377 (80.6) | |
| Positive | 305 (19.2) | 26 (21.7) | 331 (19.4) | |
| Not tested | 274 | 20 | 294 | |
Data are presented as mean (standard deviation) or number (percentage), unless otherwise indicated.
BMI, body mass index; GBS, group B streptococcus.
a
Comparisons between the groups were evaluated using the 2-sample t test for maternal age, the Wilcoxon rank-sum test for maternal education, gravida, and parity, and the chi-square test or Fisher exact test for the remaining categories.
Theiler. Clinical outcomes after COVID-19 vaccination in pregnancy. Am J Obstet Gynecol MFM 2021.