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. 2021 Apr 2;24(8):634–644. doi: 10.1093/ijnp/pyab016

Table 2.

Regional activations to outcomes in correlation with CCQ score at voxel P < .001 and cluster-level P < .05 whole-brain corrected for familywise error of multiple comparisons

Volume (mm3) Peak voxel MNI coordinates (mm) Side Identified brain region
(Z) x y z
Dollar win > nil (positive correlation with CCQ)
4509 4.82 33 23 −11 R Insula
7263 4.41 48 5 43 R Precentral G
3402 4.36 6 26 43 L/R SMA
Dollar win > nil (negative correlation with CCQ)
None
Cent win > nil (positive correlation with CCQ)
None
Cent win > nil (negative correlation with CCQ)
None
Dollar win > cent win (positive correlation with CCQ)
None
Dollar win > cent win (negative correlation with CCQ)
None
Dollar loss > nil (positive correlation with CCQ)
3672 4.49 33 20 −6 R Insula
4887 4.01 −51 −73 1 L Occipital cortex
3294 3.84 33 −61 −11 R Occipital cortex
Dollar loss > nil (negative correlation with CCQ)
None
Cent loss > nil (positive correlation with CCQ)
5670 5.18 51 38 13 R Inferior/middle frontal G
5508 4.71 45 20 −5 R Insula
12 123 4.51 48 −43 58 R Inferior parietal gyrus
Cent loss > nil (negative correlation with CCQ)
None
Dollar loss > cent loss (positive correlation with CCQ)
None
Dollar loss > cent loss (negative correlation with CCQ)
None
Dollar win > dollar loss (positive correlation with CCQ)
None
Dollar win > dollar loss (negative correlation with CCQ)
None
Cent win > cent loss (positive correlation with CCQ)
None
Cent win > cent loss (negative correlation with CCQ)
None

Abbreviations: CCQ, Cocaine Craving Questionnaire; G, gyrus; R/L, right/left; SMA, supplementary motor area.