TABLE 4.

Compliance with colistin dosing recommendations in paediatric and adult patients.

Recommendations	Number of paediatric patients (N = 16)	Number of adult patients (N = 27)
Obtain appropriate culture prior to the initiation of colistin therapy (blood cultures used)	15	13
Prescription of loading dose (LD)	1	22
Prescription of appropriate LD	Not recommended	18
Prescription of appropriate maintenance dosing (MD)		Because of the lack of eGFR data from the records reviewed, assessment on compliance to appropriate maintenance doses in adult patients could not be made
Neonates 50 000–120 000 IU/kg/day	7
Infants and children 75 000–150 000 IU/kg/day	2
Others (different to guideline†)	7

^†, Labuschagne Q, Schellack N, Gous A, et al. COLISTIN: Adult and paediatric guideline for South Africa, 2016. S Afr J Infect Dis. 2016;31(1):3–7. https://doi.org/10.4102/sajid.v31i1.95

LD, loading dose; eGFR, estimated glomerular filtration rate.