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. Author manuscript; available in PMC: 2021 Aug 20.
Published in final edited form as: Eur Respir J. 2021 Jul 1;58(1):2003988. doi: 10.1183/13993003.03988-2020

FIGURE 1.

FIGURE 1

ACE2 and TMPRSS2 mRNA expression in human lungs. a) Uniform manifold approximation and projection projections (UMAP) of the single-cell RNA data obtained from human donor lungs from individuals without lung disease (n=3). Note colour-coded populations of specific cell types, as noted, including airway epithelial cell types identified through unsupervised clustering. b–d) UMAP and violin plots of normalised expression of SCGB1A1, a marker of b) airway epithelial cells, c) ACE2 and d) TMPRSS2 in the identified cell type; colocalisation with SCB1A1 is indicated by arrows. ATI: alveolar type I cells; ATII: alveolar type II cells.