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. 2021 Aug 6;11:686044. doi: 10.3389/fonc.2021.686044

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Copyright © 2021 Yang, Li, Qin, Zhang, Zhao, Wang, Huang and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Establishment of a prognostic model of FRGs in the TCGA cohort. (A) A nine-gene signature was generated by Multivariate Cox regression analysis. (B) Distribution of signature-based risk scores. (C) The differences in the expression of the prognostic signature in different risk groups. (D) Survival status of high-risk and low-risk patients. (E) Kaplan–Meier curves indicated that the OS in the high-risk group was markedly poorer than that in the low-risk group (p < 0.0001). (F) Time-dependent ROC curve analysis for measuring the prognostic performance of the signature-based risk score on OS.