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. 2021 Aug 6;12:660397. doi: 10.3389/fimmu.2021.660397

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Copyright © 2021 Jiang, Zhang, Zhang, Lu, Sun, Wu, Ding and Huang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A–C) Representative images of GARP, PD-L1, and CTLA-4 staining in tissue microarray sections of tumor tissues. (D–F) The relationships between GARP and PD-L1 expression, GARP and CTLA-4 expression, and PD-L1 and CTLA-4 expression. (G–I) GARP expression was correlated with CD80, CD86, and IL-10 expression in the TISIDB database. (J) Protein interaction network in the STRING online database. CD274: PD-L1. (K) KEGG pathway analysis revealed 10 positively correlated pathways.