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. 2021 Aug 6;9:704048. doi: 10.3389/fbioe.2021.704048

TABLE 1.

Types of additive manufacturing processes and their general features.

AM technique Process Compatible materials Advantages Disadvantages
Fused deposition modeling (FDM) Extrusion-based PLA PCL β-TCP High mechanical strength. No excess material inside scaffold. Thermal processing. Low printing resolution (>100 μm).
Stereolithography apparatus (SLA) Laser-assisted HA CA Cell and bioink carrier potential. Internal resolution. Limited material diversity.
Selective laser sintering (SLS) Laser-assisted PCL PLA HA No support structure necessary Thermal processing
Three-dimensional printing (3DP) Binder jetting PCL No heat or support structure necessary. Low mechanical strength.
Melt electrospinning Fiber-based PCL Tunable fiber thickness (<20 μm). High architectural control. Limited material diversity.

PLA, polylactic acid; PCL, polycaprolactone; TCP, tricalcium phosphate; HA, hydroxyapatite; CA, ceramic acrylate.