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. 2021 Aug 6;12:725341. doi: 10.3389/fphar.2021.725341

FIGURE 4.

FIGURE 4

OPLS-DA plot of absolute quantitation of BAs (A). Volcano plot of absolute quantitation of BAs (B). Heatmap of selected BAs that were significantly changed in the volcano plot (C). After analysis by binary logic regression, five BA biomarkers were visualized in the form of box plots (D). The ROC curve of the above five biomarkers and the diagnostic panel (E). The prediction accuracy of the diagnostic panel is shown by a heatmap (F).