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. 2021 Aug 6;9:715093. doi: 10.3389/fcell.2021.715093

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Copyright © 2021 Helle, Ampuja, Dainis, Antola, Temmes, Tolvanen, Mervaala and Kivelä.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characterization of hiPS-CM clusters. (A) Volcano plot of altered genes in atrial type hiPS-CMs (CM Atrial-cluster) compared to ventricular type hiPS-CMs (CM Ventricular-cluster). (B) Expression of general CM genes, atrial CM, and ventricular CM genes in the four hiPS-CM clusters. (C) Representative action potential morphologies of atrial and ventricular hiPS-CMs. All scRNAseq data presented in the figure consists of combined data from HEL47.2 and HEL24.3 lines.