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. 2021 Aug 6;9:711487. doi: 10.3389/fbioe.2021.711487

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Copyright © 2021 De Rose, Kuprat, Isupov, Reinhardt, Schönheit and Littlechild.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A diagram showing the D-mannose sugar bound in the active site of TsLI with the manganese ion (shown in red) co-ordinated to the three histidines H75, H77 and H143, one glutamic acid E88, and the manganese ion.