Table 3. GSEA of the NEDD4L-related low risk group in TCGA_KIRC.
| MSigDB collection | Gene set name | NES | NOM p-value |
|---|---|---|---|
| c2.cp.v6.2.symbols.gmt | ERBB signaling pathway | 1.812 | 0.002 |
| Vasopressin regulated water reabsorption | 1.713 | 0.012 | |
| Propanoate metabolism | 1.708 | 0.041 | |
| Neurotrophin signaling pathway | 1.660 | 0.008 | |
| Ubiquitin mediated proteolysis | 1.653 | 0.018 | |
| RNA degradation | 1.650 | 0.008 |
Notes.
- NES
- normalized enrichment score
- NOM
- nominal
- FDR
- false discovery rate
Gene sets with NOM p-value < 0.05 and FDR q-value < 0.25 are considered as significant.