Table 1.
Potential targets of miR-9, miR-98, miR-223 and miR-214 involved in COVID19 pathogenesis.
| Gene | miRNA | Full name of the genes |
|---|---|---|
| IL6 | miR-98-5p,miR-223-3p, miR-9-5p | Interleukin 6 |
| IL6R | miR-98-5p | Interleukin 6 receptor |
| IL10 | miR-98-5p | Interleukin 10 |
| STAT2 | miR-98-5p,miR-214-3p, | Signal transducer and activator of transcription 2 |
| miR-223-3p | ||
| STAT3 | miR-98-5p | Signal transducer and activator of transcription 3 |
| IFNAR1 | miR-98-5p,miR-98-3p, miR-9-3p, miR-214-3p | Interferon alpha and beta receptor subunit 1 |
| IFNGR1 | miR-98-5p, miR-9-3p | Interferon gamma receptor 1 |
| PIAS4 | miR-98-5p | Protein inhibitor of activated STAT 4 |
| CCL3 | miR-98-5p | C-C motif chemokine ligand 3 |
| EDA | miR-98-5p | Ectodysplasin A |
| LYN | miR-98-5p, miR-223-3p | LYN proto-oncogene, Src family tyrosine kinase |
| PLCG2 | miR-98-5p | Phospholipase C gamma 2 |
| TAB2 | miR-98-5p,miR-98-3p, miR-9-3p, miR-214-5p | TGF-beta activated kinase 1/MAP3K7 binding protein 2 |
| BIRC3 | miR-98-5p | Baculoviral IAP repeat containing 3 |
| IKBKE | miR-98-5p | Inhibitor of nuclear factor kappa B kinase subunit epsilon |
| BCL2 | miR-98-5p, miR-9-5p | B-cell lymphoma 2 |
| BCL2L1 | miR-98-5p | BCL2 Like 1 |
| NFKB2 | miR-98-5p | Nuclear factor kappa B subunit 2 |
| LTBR | miR-98-5p | Lymphotoxin beta receptor |
| TLR8 | miR-98-5p | Toll like receptor 8 |
| TRAF1 | miR-98-5p | TNF receptor associated factor 1 |
| TRIM25 | miR-98-3p, miR-223-3p | Tripartite motif containing 25 |
| miR-214-5p, miR-9-5p | ||
| AGTR1 | miR-98-3p, miR-223-3p | Angiotensin II receptor type 1 |
| IL4R | miR-98-3p | Interleukin 4 receptor |
| IL6ST | miR-223-3p,miR-223-5p, miR-9-5p | Interleukin 6 signal transducer |
| STAT1 | miR-223-3p, miR-9-3p | Signal transducer and activator of transcription 1 |
| STAT5A | miR-223-3p | Signal transducer and activator of transcription 5A |
| ERC1 | miR-223-3P,miR-214-3p | ELKS/RAB6-interacting/CAST family member 1 |
| NFKBIA | miR-223-3p | NFKB inhibitor alpha |
| PARP1 | miR-223-3p | Poly(ADP-ribose) polymerase 1 |
| TLR8 | miR-223-3p, miR-98-5p | Toll like receptor 8 |
| ICAM1 | miR-223-3p | Intercellular adhesion molecule 1 |
| EDA2R | miR-223-5p | Ectodysplasin A2 receptor |
| IFNA21 | miR-223-5p | Interferon alpha 21 |
| MYD88 | miR-223-5p,miR-214-5p | Myeloid differentiation primary response 88 |
| TRAF5 | miR-223-5p | TNF receptor associated factor 5 |
| TNFSF14 | miR-223-5p | TNF superfamily member 14 |
| TLR7 | miR-223-5p,miR-9-5p | Toll like receptor 7 |
| RIPK1 | miR-223-5p, miR-9-5p | Receptor interacting serine/threonine kinase 1 |
| IL17D | miR-9-5p | Interleukin 17D |
| JAK1 | miR-9-5p | Janus kinase 1 |
| JAK3 | miR-9-5p, miR-214-5p, | Janus kinase 3 |
| miR-9-3p | ||
| STAM | miR-9-5p | Signal transducing adaptor molecule |
| PIAS3 | miR-9-5p, miR-214-5p | Protein inhibitor of activated STAT 3 |
| EP300 | miR-9-5p | E1A binding protein p300 |
| KLHDC10 | miR-9-5p | Kelch domain containing 10 |
| TRAF3 | miR-9-5p | TNF receptor associated factor 3 |
| TRAM1 | miR-9-5p | Translocation associated membrane protein 1 |
| NFKB1 | miR-9-5p | Nuclear factor kappa B subunit 1 |
| CFLAR | miR-9-5p | CASP8 and FADD like apoptosis regulator |
| TAB3 | miR-9-5p | TGF-beta activated kinase1 and MAP3K7 binding protein 3 |
| IL17A | miR-9-3p | Interleukin 17A |
| IRAK4 | miR-214-3p | Interleukin 1 receptor associated kinase 4 |
| TRAF2 | miR-214-5p | TNF receptor associated factor 2 |
| LTA | miR-214-5p | Lymphotoxin alpha |
| CARD14 | miR-214-3p | Caspase recruitment domain family member 14 |
| TRADD | miR-214-3p | TNFRSF1A associated via death domain |