Figure 1.

Schematic demonstrating relationships between retinal neural and vascular pathology with visual function for consideration in a revised severity scale for diabetic retinal disease. Background shading represents the context of systemic health status including, but not limited to variables such as glycemic control, blood pressure, lipids and the presence of comorbidities. (A) represents an eye with excellent vision and minimal to mild retinal neural or vascular abnormalities in a patient with good systemic health. (B) is an eye with moderate vision loss, e.g. from diabetic macular edema, and combined neurovascular disease in an individual with some systemic health issues. (C) represents an eye with late stage disease, e.g. from a macular traction retinal detachment, and severe vision loss in a patient with poor overall systemic health.