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. 2021 May 17;2021:112–121.

Fig. 1.

Fig. 1.

Heterogeneity analysis at three levels of granularity: (A) cohort-level analysis enables the identification of frequently co-occurring comorbidities; (B) subgroup-level analysis enables the measurement of comparative risk of patient subgroups and how they differ in their characteristics; and (C) patient-level analysis helps to determine whether a specific patient is similar or dissimilar to other patients in their respective subgroup.