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. 2021 Aug 20;16(8):e0256396. doi: 10.1371/journal.pone.0256396

Fig 3. Cohort 1 and Cohort 2: Comparison of post-5th (pre-CHMI) IFN-γ, IL2 and IFN-γ+IL2 responses to SPZ.

Fig 3

Cohort 1: protected (n = 6), non-protected (n = 5); Cohort 2: protected (n = 9), non-protected (n = 1). Post-5th (pre-CHMI) Cohort 1 and Cohort 2 IFN-γ, IL2 and IFN-γ+IL2 responses to SPZ of each subject are protected (P) or not protected (NP) to CHMI#1. Horizontal black lines separate subjects with positive (above) or negative (below) responses. Panel A: Cohort 1: numbers of protected subjects with higher activities than the highest responding non-protected subject were: IFN-γ (2/6), IL2 (4/6) and IFN-γ+IL2 (4/6). Panel B: Cohort 2: numbers of protected subjects with higher activities than the highest responding non-protected subject were: IFN-γ (6/9), IL2 (6/9) and IFN-γ+IL2 (4/9).