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. 2021 Aug 20;16(8):e0256522. doi: 10.1371/journal.pone.0256522

Table 1. Baseline characteristics, follow-up, and survival according to primary kidney disease.

Type 2 diabetes Type 1 diabetes Glomerulo-nephritis Polycystic kidney disease Nephro-sclerosis Other or unknown diagnoses All patients P value
Number of patients (%) 1720 (19.8) 1315 (15.1) 1207 (13.9) 826 (9.5) 539 (6.2) 3089 (35.5) 8696 (100)
Kidney biopsy, % 13.5 7.6 86.7 1.8 27.9 29.1 28.3 <0.001
Male gender, % 69.0 65.5 71.6 51.7 72.7 62.8 65.2 <0.001
Median age at KRT start in years (25 th –75 th percentile) 67.0 (60.5–73.0) 47.3 (39.2–55.6) 59.7 (46.8–69.2) 57.9 (51.1–64.8) 71.8 (62.5–78.5) 67.5 (56.3–75.8) 63.2 (51.6–72.2) <0.001
Median follow–up time in years (25 th –75 th percentile) 2.65 (1.28–4.78) 3.87 (1.68–8.61) 5.00 (1.97–9.56) 5.97 (2.78–10.58) 2.67 (1.21–5.16) 2.95 (1.12–6.20) 3.41 (1.41–7.02) <0.001
Hemodialysis as the first treatment modality, % 83.1 55.6 68.2 77.7 76.1 81.1 75.2 <0.001
Kidney transplantation during follow-up, N (N/100 patient-years) 186 (3.1) 628 (8.7) 609 (8.1) 557 (9.6) 105 (5.1) 739 (5.6) 2824 (6.8) <0.001
Median survival in years (95% CI) 3.26 (3.08–3.43) 7.95 (6.83–9.07) 12.23 (10.88–3.57) 15.41 (N/A) 4.02 (3.53–4.51) 4.45 (4.19–4.72) 5.39 (5.18–5.60) <0.001
Number of deaths (N/100 patient-years) 1294 (21.6) 619 (8.6) 445 (5.9) 236 (4.1) 342 (16.7) 1857 (14.0) 4793 (11.5) <0.001
Cardiovascular cause of death, % 46.8 57.0 44.0 37.7 45.3 31.8 41.5 <0.001

95% CI, 95% confidence interval.