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. 2021 Aug 20;16(8):e0256429. doi: 10.1371/journal.pone.0256429

Table 1. The characteristics of included RCTs.

First author Type of COVID-19 Sample size (M/F) Age (yrs) Intervention Control Duration Outcome measures
Duan C [15] mild T:82(39/43) C:41(23/18) T:51.99±13.88 C:50.29±13.17 Jinhua Qinggan granule and conventional therapy Conventional therapy 5 days ⑤+⑦
Fu [16] mild/ moderate T:32(17/15) C:33(19/14) T:43.26±7.15 C:43.68±6.45 Toujie Quwen granule and conventional therapy Conventional therapy 10 days ①+②+③+⑤+⑥+⑦
Fu XX [17] moderate T:37(19/18) C:36(19/17) T:45.26±7.25 C:44.68±7.45 Toujie Quwen granule and conventional therapy Conventional therapy 15 days ②+③+⑤+⑥+⑦
Hu F [18] moderate T:100(49/51) C:100(55/45) T:47.00±14.06 C:49.28±11.14 Jinyinhua oral liquid and conventional therapy Conventional therapy 10 days ①+③+④+⑦
Hu K [19] mild/ moderate T:142(79/63) C:142(71/71) T:50.4±15.2 C:51.8±14.8 Lianhua Qingwen capsule and conventional therapy Conventional therapy 14 days ①+②+③+④+⑤+⑦
Qiu M [20] moderate T:25(13/12) C:25(14/11) T:53.35±18.35 C:51.32±14.62 Maxing Xuanfei Jiedu Decoction and conventional therapy Conventional therapy 10 days ①+③+⑤
Sun HM [21] mild/ moderate T:32(17/15) C:25(11/14) T:45.4±14.10 C:42.0±11.70 Lianhua Qingke granule and conventional therapy Conventional therapy 14days ①+③+⑤
Yang MB [22] moderate T:26(16/10) C:23(9/14) T:50.35±13.37 C:47.17±16.57 Reyanning mixture and conventional therapy Conventional therapy 7 days ③+④+⑤+⑥+⑦
Yu P [23] mild/ moderate T:147(82/65) C:148(89/59) T:48.27±9.56 C:47.25±8.67 Lianhua Qingwen granule and conventional therapy Conventional therapy 7 days ①+②+③+⑤+⑥+⑦
Zhang CT [24] moderate T:22(9/13) C:23(10/13) T:53.7±3.5 C: 55.6±4.2 Jiawei Dayuan Decoction and conventional therapy Conventional therapy 7 days ①+⑤+⑥+⑦
Zhang YL [25] moderate T:80(50/30) C:40(23/17) T:53.4±13.70 C:52.0±14.10 Jinyinhua oral liquid and conventional therapy Conventional therapy 10 days ③+⑤+⑦
Zhou WM [26] moderate T:52(32/20) C:52(28/24) T:52.47±10.99 C:51.11±9.87 diammonium glycyrrhizinate and conventional therapy Conventional therapy 14 days ②+⑥+⑦

①: Lung CT; ②: Clinical cure rate; ③: Rate of conversion to severe cases; ④: Virus nucleic acid testing; ⑤: Clinical symptoms; ⑥: Inflammatory biomarkers; ⑦: Adverse events.