Table 4. Adjusted median bacterial DNA levels between non-cases and the stages of gastric cancer lesions.
Median (p-value for Mann-Whitney test) | |||||||||
---|---|---|---|---|---|---|---|---|---|
Non-case | IA (n = 3) | IB (n = 9) | IIA (n = 11) | IIB (n = 7) | IIIA (n = 29) | IIIB (n = 19) | IIIC (n = 6) | IV (n = 108) | |
Saliva | |||||||||
A. actinomycetemcomitans (Aa) | 0.9280 | 2.6027
(<0.001) |
2.0648
(<0.001) |
2.2591
(<0.001) |
2.3052
(<0.001) |
2.2635
(<0.001) |
2.2482
(<0.001) |
2.4598
(<0.001) |
2.4425
(<0.001) |
P. gingivalis (Pg) | 2.0568 | 1.5840
(0.0061) |
1.3652
(<0.001) |
1.3757
(<0.001) |
1.2080
(<0.001) |
1.3358
(<0.001) |
1.3113
(<0.001) |
1.3711
(0.001) |
1.4472
(<0.001) |
T. denticola (Td) | 19.0366 | 4.4287
(<0.001) |
3.8353
(<0.001) |
3.5581
(<0.001) |
3.7817
(<0.001) |
4.0994
(< 0.001) |
3.6386
(<0.001) |
3.1388
(<0.001) |
3.6437
(<0.001) |
T. forsythia (Tf) | 7.0225 | 2.1872
(<0.001) |
1.9866
(<0.001) |
2.0532
(<0.001) |
2.0947
(<0.001) |
1.9911
(< 0.001) |
2.0538
(<0.001) |
1.9860
(<0.001) |
2.0551
(<0.001) |
S. sobrinus (Sb) | 0.5314 | 3.0582
(<0.001) |
3.1276
(<0.001) |
3.4207
(<0.001) |
3.0464
(<0.001) |
3.0885
(<0.001) |
3.4207
(<0.001) |
3.0265
(<0.001) |
3.2912
(<0.001) |
S. mutans (Sm) | 9.4285 | 4.9918
(<0.001) |
5.0705
(<0.001) |
5.1590
(<0.001) |
5.2186
(<0.001) |
5.0729
(<0.001) |
5.0771
(<0.001) |
5.6576
(<0.001) |
5.2480
(<0.001) |
Plaque | |||||||||
A. actinomycetemcomitans (Aa) | 1.5863 | 1.8021
(0.0150) |
1.8276
(0.0011) |
1.7256
(0.0013) |
1.8058
(0.0014) |
1.7469
(<0.001) |
1.6996
(<0.001) |
1.7489
(0.0068) |
1.7056
(<0.001) |
P. gingivalis (Pg) | 10.5563 | 8.0431
(<0.001) |
6.1636
(<0.001) |
6.5555
(<0.001) |
7.2602
(<0.001) |
6.8336
(<0.001) |
5.7006
(<0.001) |
7.2513
(<0.001) |
6.5161
(<0.001) |
T. denticola (Td) | 1.8279 | 1.5064
(0.0037) |
1.5586
(<0.001) |
1.4896
(<0.001) |
1.4279
(<0.001) |
1.4814
(<0.001) |
1.5077
(<0.001) |
1.4538
(<0.001) |
1.5074
(<0.001) |
T. forsythia (Tf) | 6.2397 | 3.0745
(<0.001) |
3.3550
(<0.001) |
3.2835
(<0.001) |
3.2500
(<0.001) |
3.5000
(<0.001) |
3.6156
(<0.001) |
3.4892
(<0.001) |
3.5950
(<0.001) |
n = number of patients with gastric cancer in each stage.