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Patients classified to the hyperinflammatory subphenotype by the four-variable parsimonious model had higher levels of all other plasma biomarkers not included in the four-variable model. Biomarker values are displayed on logarithmic scale. ****p < 0.0001. BDG = 1-3-beta-D-glucan, IL = interleukin, RAGE = receptor of advanced glycation end product, ST-2 = suppression of tumorigenicity-2.
