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. 2021 Aug 19;3(8):e0518. doi: 10.1097/CCE.0000000000000518

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Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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Figure 5. — Hyperinflammatory patients in the validation cohort had worse 30-d survival compared with hypoinflammatory patients. Kaplan-Meier curves for 30-d survival for each subphenotype, as derived by the four-variable parsimonious model. p values for differences between subphenotypes were obtained with a log-rank test. Adjusted hazard ratios (HRs) with 95% CIs are displayed for the effects of the hyperinflammatory subphenotype, as derived from a multivariate Cox proportional hazards model adjusted for age and clinical category of acute respiratory failure (coronavirus disease 2019 [COVID-19] acute respiratory distress syndrome [n = 40], COVID-19 pneumonia not intubated [n = 40], and non-COVID acute respiratory failure [n = 59]).