Table 1.
Baseline characteristics and laboratory findings of 499 patients with COVID-19.
| Characteristics | All patients (n = 499) |
Survivors (n = 464) |
Death (n = 35) |
p-Value | |
|---|---|---|---|---|---|
| Age (mean (SD)) | 59 (15) | 58 (15) | 72 (11) | <0.001 | |
| Gender = m (%) | 253 (50) | 234 (50) | 19 (54) | 0.791 | |
| Comorbidities, n (%) | |||||
| Hypertension | 185 (37.1) | 168 (36.2) | 17 (48.6) | 0.201 | |
| Heart failure | 19 (3.8) | 17 (3.7) | 2 (5.7) | 0.878 | |
| Diabetes | 80 (16.0) | 73 (15.7) | 7 (20.0) | 0.671 | |
| Coronary heart disease | 34 (6.8) | 28 (6.0) | 6 (17.1) | 0.030 | |
| Chronic renal disease | 25 (5.0) | 19 (4.1) | 6 (17.1) | 0.003 | |
| Chronic liver disease | 14 (2.8) | 13 (2.8) | 1 (2.9) | 1.000 | |
| Laboratory findings | Normal range | ||||
| TNI, ng/ml (median [IQR]) | 0–0.04 | 0.01 [0.01, 0.01] | 0.01 [0.01, 0.01] | 0.04 [0.02, 0.15] | <0.001 |
| Creatinine, μmol/L (mean (SD)) | 64–104 | 84 (121) | 76 (86) | 182 (320) | <0.001 |
| MYO, ng/ml (median [IQR]) | 0–80 | 6 [3, 11] | 6 [3, 9] | 134 [24, 605] | <0.001 |
| CK-MB, ng/ml (median [IQR]) | 0–6.36 | 1.1 [0.8, 1.7] | 1.0 [0.7, 1.6] | 4.7 [2.3, 10.5] | <0.001 |
| D_DIMER, mg/L (median [IQR]) | 0–0.55 | 0.6 [0.2, 1.4] | 0.5 [0.2, 1.1] | 4.5 [1.80, 7.3] | <0.001 |
| Leukocyte counts, *109/L (mean (SD)) | 3.5–9.5 | 6.4 (3.0) | 6.1 (2.6) | 10.3 (4.7) | <0.001 |
| Hemoglobin, g/L (mean (SD)) | 130–175 | 121 (21) | 121 (20) | 112 (28) | 0.011 |
| Lymphocyte rate (mean (SD)) | 20–50% | 25% (11) | 26% (10) | 8% (6) | <0.001 |
| Lymphocyte count, *109/L (mean (SD)) | 1.1–3.2 | 1.4 (0.6) | 1.5 (0.6) | 0.7 (0.4) | <0.001 |
| Alanine aminotransferase, IU/L (median [IQR]) | 9–50 | 24 [15, 39] | 23 [15, 38] | 34 [19, 45] | 0.043 |
| Aspartate aminotransferase, IU/L (median [IQR]) | 15–40 | 21 [16, 30] | 20 [16, 28] | 38 [27, 66] | <0.001 |
| Albumin, g/L (mean (SD)) | 40–55 | 36 (5) | 36 (4) | 30 (6) | <0.001 |
| C-reactive protein, mg/L (median [IQR]) | 0–4 | 1.6 [0.5, 10.0] | 1.2 [0.5, 7.4] | 51.1 [12.2, 75.9] | <0.001 |
| BNP, pg/ml (median [IQR]) | 0–100 | 10 [10, 35] | 10 [10, 29] | 115 [44, 308] | <0.001 |
| Procalcitonin, ng/ml (median [IQR]) | 0–0.05 | 0.04 [0.03, 0.07] | 0.04 [0.03, 0.07] | 0.43 [0.15, 1.19] | <0.001 |
TNI, troponin; MYO, myoglobin; CK-MB, creatinine kinase-myocardial band; BNP, B-type natriuretic peptide; IQR, inter-quartile range; SD, standard deviation.