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. 2021 Aug 12;2021:1736819. doi: 10.1155/2021/1736819

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Copyright © 2021 Xirui Ma et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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PANTR1 mediates HCC cell functions via sponging miR-587. (a) Transfection efficiencies in HepG2 and Hep3B were analyzed by qRT-PCR. (b and c) CCK-8 assays were conducted to evaluate the cell proliferation abilities of each treated HepG2 and Hep3B cells. (d, e) Flow cytometer assay was performed to assess the cell apoptosis rate of each treated HepG2 and Hep3B cells. (f, g) Cell migration abilities were detected by performing Transwell migration assays. Comparative statistics are shown. Scale bars: 20 μm. (h–j) The Warburg effect phenomenon-related lactate production (h), glycolysis rates (i), and ATP levels (j) in treated cells were assessed. Data are shown as the mean ± standard deviation (n = 3). ^∗P < 0.05, ^∗∗P < 0.01, and ^∗∗∗P < 0.001.