Table 1.

The relationship between TDO2 expression and clinicopathological features in 116 patients with primary HCC.

Features	Total	TDO2 expression		P value
		Normal expression	Low expression
Sex
Male	95	43	52	0.324
Female	21	12	9
Age (years)
≤50	52	23	31	0.254
>50	64	34	30
ALT
<70	106	49	57	0.615
≥70	10	6	4
AST
<70	101	47	54	0.830
≥70	15	8	7
Serum AFP (ng/ml)
<400	62	25	37	0.101
≥400	54	30	24
Tumor size (cm)∗
≤5	39	26	13	0.011
>5	77	32	45
Tumor number
Single	90	59	41	0.127
Multiple	26	11	15
BCLC stage
0+A	75	48	27	0.019
B+C	41	17	24
TNM stage
I + II	86	46	40	0.027
III + IV	30	9	21
Differentiation
Well/moderate	73	40	33	0.038
Poor	43	15	28
Vascular invasion
Yes	23	7	16	0.069
No	93	48	45
Tumor capsule
Absent	55	26	29	0.977
Present	61	29	32
Recurrence
Yes	58	22	36	0.041
No	58	33	25