Table 2.
Biochemical parameters (mean ± SD).
| Parameters | TT (n = 324) | TC+CC (n = 39) | |||
|---|---|---|---|---|---|
| Basal | 3 months | Basal | 3 months |
P values -Time TT -Basal genotype -Time TC+CC -3 months genotype |
|
| Glucose (mg/dL) | 101.8 ± 4.1 | 97.5 ± 7.0 | 97.7 ± 8.0 | 96.9 ± 7.1 |
P = 0.12 P = 0.51 P = 0.18 P = 0.40 |
| Total cholesterol (mg/dL) | 205.1 ± 4.7 | 194.9 ± 4.2$ | 209.2 ± 4.3 | 198.4 ± 4.2$ |
P = 0.02 P = 0.50 P = 0.03 P = 0.39 |
| LDL-cholesterol (mg/dL) | 127.9 ± 9.1 | 114.8 ± 5.2# | 130.5 ± 6.0 | 109.2 ± 5.1# |
P = 0.01 P = 0.49 P = 0.02 P = 0.35 |
| HDL-cholesterol (mg/dL) | 50.8 ± 1.6 | 52.2 ± 1.9 | 53.9 ± 2.1 | 51.7 ± 1.8 |
P = 0.13 P = 0.34 P = 0.59 P = 0.43 |
| Triglycerides (mg/dL) | 120.2 ± 8.0 | 100.9 ± 9.2∗ | 131.6 ± 6.2+ | 127.8 ± 5.1+ |
P = 0.02 P = 0.01 P = 0.31 P = 0.02 |
| Insulin (mUI/L) | 16.7 ± 1.1 | 13.1 ± 1.2& | 13.3 ± 3.2 | 11.8 ± 2.9 |
P = 0.03 P = 0.41 P = 0.13 P = 0.49 |
| HOMA-IR | 4.6 ± 1.1 | 3.1 ± 1.0∗∗ | 3.0 ± 0.9 | 2.7 ± 1.1 |
P = 0.01 P = 0.38 P = 0.12 P = 0.49 |
| CRP | 4.4 ± 1.1 | 4.2 ± 1.0 | 4.5 ± 2.0 | 4.3 ± 2.1 |
P = 0.21 P = 0.31 P = 0.39 P = 0.40 |
HOMA-IR: homeostasis model assessment; CRP: C reactive protein. Statistical differences P < 0.05, in each genotype group (total cholesterol$, LDL-cholesterol#, insulin&, HOMA IR∗∗) (triglyceride between genotypes+). First P: significance of dietary intervention after 3 months in TT genotype; second P: significance between TT genotypes vs. TC+CC baseline values; third P: significance of dietary intervention after 12 weeks in TC+CC genotype; fourth P: significance between TT genotypes vs. TC+CC posttreatment values.