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. 2021 Aug 21;154:104556. doi: 10.1016/j.ijmedinf.2021.104556

Table 2.

Derivative variables and their univariate and multivariate analysis with mortality during hospital stay.

Univariate Multivariate
Derivatives for machine learning Variables p-value HR 95%CI p-value HR 95%CI
Total No. Comorbidities Range (0–6) <0.001* 1.44 1.27–1.64 <0.001* 1.301 1.14–1.49
More than 2 comorbidities 499 <0.001* 2.28 1.59–3.28 <0.001* 1.788 1.23–2.61
Total No. symptoms Range (0–6) 0.379 1.08 0.92–1.27 0.439 1.066 0.91–1.26
Total No. Treatments received Range (0–6) <0.001* 1.31 1.14–1.51 <0.05* 1.268 1.11–1.46
CR or BUN 517 <0.001* 0.31 0.21–0.46 <0.001* 0.356 0.24–0.54
HB or HCT 883 <0.05* 0.55 0.35–0.87 <0.05* 0.562 0.36–0.89
PLT or INR 460 <0.001* 2.21 1.55–3.16 <0.001* 2.087 1.47–2.98
PT or INR 502 <0.001* 0.46 0.33–0.66 <0.001* 0.414 0.29–0.6
TLC or LYMP 882 <0.001* 0.18 0.08–0.4 <0.001* 0.186 0.09–0.43
TLC or NEU 1085 <0.05* 0.2 0.07–0.61 <0.05* 0.18 0.06–0.57
Total No. laboratory abnormalities Range (0–17) <0.001* 1.22 1.16–1.3 <0.001* 1.216 1.15–1.3