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. 2021 Aug 21;36(10):109679. doi: 10.1016/j.celrep.2021.109679

Figure 5.

Figure 5

Post-exposure therapeutic potency of MD65, BL6, and BLN14 in K18-hACE2 mice infected with various SARS-CoV-2 strains

The SARS-CoV-2 strains are indicated in the left vertical lane and the administered antibodies in the legends within each individual panel (colored differently). A single dose of 1 mg Ab/animal of each indicated mAb (n = 6 per experimental group) or PBS for the control groups (n ≥ 7) was administered at day 2 after viral infection. Left panels: body weight profiles. Body weight is displayed as percentage change of initial weight (average ± SEM). Only data of the first 6 days are presented in the control groups exhibiting significant mortality. Right panels: Kaplan-Meier survival curves.