Table 1.
Patients’ characteristics of FMR patients without (−) MR recurrence and with (+) MR recurrence at 1 year follow-up after PMVR
| − MR recurrence (n = 195) |
+ MR recurrence (n = 25) |
p value | |
|---|---|---|---|
| Clinical characteristics | |||
| Age (years) | 77.0 (71.0, 82.0) | 73.0 (68.5, 79.0) | 0.179 |
| Female gender, n (%) | 74 (37.9) | 8 (32.0) | 0.563 |
| Logistic EuroSCORE (%) | 20.5 (13.0, 33.3) | 25.0 (13.0, 38.8) | 0.479 |
| ICM, n (%) | 127 (65.1) | 14 (56.0) | 0.370 |
| DCM, n (%) | 58 (29.7) | 10 (40.0) | 0.296 |
| Coronary artery disease, n (%) | 131 (67.2) | 14 (56.0) | 0.267 |
| Prior CABG, n (%) | 55 (27.7) | 10 (40.0) | 0.227 |
| Prior valve surgery, n (%) | 30 (15.4) | 5 (20.0) | 0.553 |
| Prior Stroke, n (%) | 17 (8.7) | 2 (8.0) | 0.904 |
| COPD, n (%) | 38 (19.5) | 4 (16.0) | 0.676 |
| Diabetes, n (%) | 46 (23.6) | 4 (16.0) | 0.394 |
| Atrial fibrillation, n (%) | 132 (67.7) | 18 (72.0) | 0.663 |
| Pacemaker/ICD/CRT, n (%) | 137 (70.3) | 16 (64.0) | 0.522 |
| Peripheral artery disease, n (%) | 29 (14.9) | 4 (16.0) | 0.882 |
| Severe tricuspid regurgitation, n (%) | 48 (24.6) | 8 (33.0) | 0.429 |
| Medication | |||
| ACE inhibitors/ARB, n (%) | 145 (74.4) | 20 (80.0) | 0.538 |
| Betablocker, n (%) | 154 (79.0) | 21 (84.0) | 0.558 |
| Diuretics, n (%) | 180 (92.3) | 24 (96.0) | 0.503 |
| Aldosterone antagonists, n (%) | 82 (42.1) | 11 (44.0) | 0.853 |
| Digitalis, n (%) | 23 (11.8) | 2 (8.0) | 0.574 |
| Laboratory assessment | |||
| Estimated GFR (ml/min) | 48 (34, 64) | 40 (31, 72) | 0.766 |
| NT-proBNP (× 1000 pg/ml | 2.94 (1.44, 5.49) | 3.05 (2.33, 5.93) | 0.333 |
| Haemoglobin (g/dl) | 12.3 (11.1, 13.4) | 12.0 (10.0 12.9) | 0.127 |
Values are n (%) or median (interquartile range)
FMR functional mitral regurgitation, MR mitral regurgitation, ICM ischemic cardiomyopathy (impaired left ventricular function that results from coronary artery disease), DCM dilative cardiomyopathy (due to non-ischemic origin), ACE angiotensin-converting enzyme, ARB angiotensin receptor blocker, CABG coronary artery bypass grafting, COPD chronic obstructive pulmonary disease, CRT cardiac resynchronization therapy, GFR glomerular filtration rate, ICD internal cardiac defibrillator, NT-proBNP brain natriuretic peptide, PMVR Percutaneous mitral valve repair
*Indicates p ≤ 0.05 between the groups