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. 2021 Mar 16;31(9):6962–6973. doi: 10.1007/s00330-021-07737-9

Table 3.

Final diagnosis of the adnexal masses according to the reference standard for the whole cohort and the random subset

Final diagnosis Whole cohort (n = 350) Random subset (n = 121)
Normal ovary, n (%) 6 (1.7)* 2 (1.6)
Benign disease, n (%) 291 (83.1) 99 (81.8)
  Ovarian
    Benign Brenner tumor 2 (0.5) 0 (0.0)
    Benign germ cell tumor 84 (24.0) 32 (26.4)
    Benign ovarian cyst 28 (8.0) 14 (11.5)
    Benign stromal tumor 29 (8.2) 8 (6.6)
    Cystadenoma 53 (15.1) 14 (11.5)
    Cystadenofibroma 16 (4.5) 5 (4.1)
    Endometrioma 68 (19.4) 22 (18.1)
    Functional cyst 3 (0.8) 1 (0.8)
    TOA/inflammation 4 (1.1) 3 (2.4)
  Non-ovarian
    Benign non-ovarian cyst# 2 (0.5) 0 (0.0)
    Leiomyoma 2 (0.5) 0 (0.0)
Borderline disease, n (%) 14 (4.0) 5 (4.1)
  Ovarian
    Serous borderline 9 (2.5) 3 (2.4)
    Mucinous borderline 5 (1.4) 2 (1.6)
Malignant disease, n (%) 39 (11.1) 15 (12.3)
  Ovarian
    Clear cell carcinoma 6 (1.7) 2 (1.6)
    Endometrioid carcinoma 5 (1.4) 2 (1.6)
    Serous carcinoma 16 (4.5) 6 (4.9)
    Mucinous carcinoma 1 (0.2) 0 (0.0)
    Transitional cell carcinoma 2 (0.5) 0 (0.0)
    Malignant germ cell tumor 3 (0.8) 3 (2.4)
    Malignant sex-cord stromal tumor 2 (0.5) 0 (0.0)
    Metastasis§ 2 (0.5) 0 (0.0)
  Non-ovarian
    Other (i.e. lymphoma) 2 (0.5) 2 (1.6)

TOA tubo-ovarian abscess

*Unless otherwise specified, data are numbers of masses, with percentages in parenthesis

#Benign non-ovarian cyst refers to paraovarian cyst or peritoneal inclusion cyst

§Two adnexal masses which were scored as primary adnexal masses resulted as metastases after histopathological assessment