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. 2020 Dec 11;42(9):1516–1523. doi: 10.1038/s41401-020-00570-8

Fig. 5. Remodeling tumor immune microenvironment.

Fig. 5

a Flow cytometric scatter-plot of IFN-γ+CD8+ T cells in the tumor. b The frequency of IFN-γ+CD8+ T cells in the tumor. c Intratumoral IFN-γ levels. The mRNA (d) and protein levels of TNF-α (e) in the tumor after treatment. f Expression of PD-L1 in the tumor cells after treatment. g The frequency of PD-L1+ cells. h The frequency of CD4+Foxp3+ Tregs in the tumor. i Flow cytometric scatter-plot of CD4+Foxp3+ regulatory T cells in the tumor. Mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001.