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. 2021 Aug 20;11:16999. doi: 10.1038/s41598-021-96562-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Levels of serum uridine after the intravenous administration of the nucleoside to rats in the control group (normoxia, n = 6) and in the group of animals with acute myocardial ischemia (AMI, n = 6). Uridine was given at a dose of 30 mg/kg five min before AMI. The determination of uridine in rat blood serum by HPLC was carried out at the following time points: 0 (background level), 5, 10, 15, 30, and 65 min after uridine administration. Data shown are the mean ± SD (n = 6). **p < 0.01 (vs. normoxia group).