Table 1.
Patient and clinical characteristics.
| Patients included | n = 5 |
|---|---|
| Age, y | 66 ± 6.6 |
| Male sex | 5 (83%) |
| Bodyweight, kg | 91.0 ± 34.3 |
| BMI | 32.1 ± 10.6 |
| SAPS II | 54 ± 17 |
| Patients on CRRT | 4 (66%) |
| Dialytic flow, ml/h | 2500 ± 341 |
| Daily balance, ml | − 155 ± 1683 |
| Albumin concentration, g/dl | 2.1 ± 0.3 |
| Cefazolin clearance, L/h | 4.3 ± 3.9 |
| Cefazolin clearance in patients with CRRT, L/h | 2.0 ± 0.4 |
| Cefazolin clearance in patients without CRRT, L/h | 8.5 ± 3.8 |
| Total cefazolin concentration, mg/L | 98.1 ± 52.6 |
| Free cefazolin concentration, mg/L | 51.1 ± 33.8 |
| Cefazolin free fraction, % | 49 ± 9 |
Data are given as mean + / − s.d. or count and percentage as indicated. Y years, kg kilogram, BMI body mass index, SAPS II Simplified Acute Physiology Score II, CRRT continuous renal replacement therapy, ml milliliter, h hour, g gram, dl deciliter, L liter, % = percentage.