Figure 3.

Vascepa reduces liver TG levels with no changes in serum lipid markers

(A–G) (A) Liver TG (n = 17,18,19) (B) liver histology using H&E staining (Scale bar 100μm) (C) average lipid droplet area (%) and (D) average size using ORO staining (E) lipid droplet size distribution using H&E staining analysis (n = 4/group) (F) hepatic injury markers (AST and ALT) levels (G) serum lipid levels (TG, cholesterol, HDL, LDL, VLDL) (n = 12,14,15). AST, aspartate aminotransferase; ALT, alanine aminotransferase; TG, triglyceride; HDL, high-density lipoprotein; LDL, low-density lipoprotein; VLDL, very low-density lipoprotein. ∗p < 0.05, ∗∗p < 0.01 vs con-HFD. All error bars ±SEM.