Fig. 3.

Downregulation of the expression of GSK3β during TDM induced odontogenesis. hDPSCs odontogenesis was induced using treated dentin matrix (TDM). (A-B) Cell migration was as indicated and detected via the transwell assay. (C-D) The expression levels of p-GSK3β in hDPSCs treated or not with TDM induction was detected by Western blotting assay. (E) The differentially expressed genes between control group and TDM TDM-treated cells, as per RNA-seq analysis are shown in the heat map. * means p<0.05 and **means p<0.01 compared with the control group.