Table 3.
Pathways impacted by TDM-treatment, as per KEGG analysis.
| KEGG pathway | Count | KEGG_ID/KO |
|---|---|---|
| Pathways in cancer | 14 | hsa:650|hsa:8322|hsa:332|hsa:3082|hsa:6387|hsa:1869|hsa:2737|hsa:8313|hsa:1870|hsa:51,176|hsa:1163|hsa:6932|hsa:2034|hsa:2252| |
| Basal cell carcinoma | 6 | hsa:650|hsa:8322|hsa:2737|hsa:8313|hsa:51,176|hsa:6932| |
| Wnt signaling pathway | 7 | hsa:8322|hsa:85407|hsa:8313|hsa:51176|hsa:27123|hsa:6932|hsa:5176| |
| Hippo signaling pathway | 7 | hsa:650|hsa:8322|hsa:85407|hsa:8313|hsa:51176|hsa:332|hsa:6932| |
| ECM-receptor interaction | 5 | hsa:3690|hsa:1292|hsa:3371|hsa:1291|hsa:6382| |
| Cytokine-cytokine receptor interaction | 8 | hsa:3592|hsa:650|hsa:55504|hsa:6387|hsa:3082|hsa:27242|hsa:7133|hsa:11009| |
| Protein digestion and absorption | 4 | hsa:1292|hsa:4311|hsa:1291|hsa:1294| |
| Mineral absorption | 3 | hsa:261,729|hsa:2495|hsa:2495| |
| PI3K-Akt signaling pathway | 7 | hsa:1291|hsa:3082|hsa:1292|hsa:3690|hsa:672|hsa:3371|hsa:2252| |
| Focal adhesion | 5 | hsa:3690|hsa:1292|hsa:3371|hsa:1291|hsa:3082| |
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | 3 | hsa:3690|hsa:51176|hsa:6932| |
| Small cell lung cancer | 3 | hsa:1870|hsa:1869|hsa:1163| |
| Rheumatoid arthritis | 3 | hsa:6387|hsa:245972|hsa:4314| |
| African trypanosomiasis | 2 | hsa:3592|hsa:2150| |