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Cubosomes-based NPs for siRNA delivery. (a) Schematic depiction of the cubic (QIIG, siRNA) phase, the inverted hexagonal (HIIsiRNA) phase, and the lamellar (LαsiRNA) phase of cationic liposomes/siRNA complexes, Reproduced with permission [177]. Copyright 2010, American Chemical Society; (b) Microfluidic synthesis of cubosomes and their formation mechanisms, Reproduced with permission [178]. Copyright 2018, American Chemical Society.
