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Typical polymers used for TOs delivery. (a) Natural–origin polymers-based NPs; (b) Synthetic polymers-based NPs; (c) Chitosan-hyaluronic acid dialdehyde nanoparticles (CS-HAD-NPs) for Bcl-2 siRNA delivery in the application of bladder cancer therapy [180]. Copyright 2021, Elsevier B.V.; (d) Schematic of core-shell structure based nanoparticles for drug delivery [181]. Copyright 2019, United States National Academy of Sciences.
