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. 2021 Jun 12;7:292–323. doi: 10.1016/j.bioactmat.2021.05.038

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© 2021 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 4 — Gold nanoparticle-based platforms for TOs delivery. (a) Spherical nucleic acids offer a different paradigm for gene regulation. Reproduced with permission [215], Copyright 2012, American Chemical Society; (b) Multidrug-loaded nanoswitch and its intracellular pH-responsive multidrug delivery and release. Reproduced with permission [233], Copyright 2019, American Chemical Society; (c) BAG3 siRNA loaded gold nanorods to improve the PTT efficiency via silencing the heat-shock response. Reproduced with permission [238], Copyright 2016, Elsevier Ltd.; (d) Nucleolin-mediated, active trafficking of AS1411-conjugated gold nanostars to the cancer cell nucleus. Reproduced with permission [241], Copyright 2012, American Chemical Society.