Fig. 3.

NIR-responsive drug delivery and photothermal therapy. (A) Temperature variations of DOX@(Fe₃O₄@PEG-PLGA) and (PB+DOX)@(Fe₃O₄@PEG-PLGA) MCs with irradiation of 808-nm NIR laser. On: turn on the laser; off: turn off the laser. (B) DOX release from (PB+DOX)@(Fe₃O₄@PEG-PLGA) MCs with and without magnetic field and irradiation of 808-nm NIR laser. (C) Infrared thermographic maps. The temperature shown in the figure represents the highest temperature and the color bar represents the relative temperature. (D) Time-dependent temperature increase in the tumor-bearing nude mice irradiated by the 808-nm NIR laser after tail vein injection with 100 μL of saline and (PB+DOX)@(Fe₃O₄@PEG-PLGA).