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. 2021 May 29;7:453–465. doi: 10.1016/j.bioactmat.2021.05.004

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© 2021 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 6 — Micro-CT and BMD of nude mice treated with photothermal therapy. (A) Micro-CT images of the right hind leg of nude mice (with tumor). (B) Micro-CT images of the right hind leg of nude mice (perspective). (C) Measurement of bone mineral density from different groups (n = 6) at 28 days. (1) (PB+DOX)@(Fe₃O₄@PEG-PLGA) MCs + NIR laser; (2) (PB+DOX)@(Fe₃O₄@PEG-PLGA) MCs; (3) PB@(Fe₃O₄@PEG-PLGA) MCs + NIR laser; (4) PB@(Fe₃O₄@PEG-PLGA) MCs; (5) DOX; (6) Saline. **p < 0.01, ***p < 0.001.