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Summary of the effect of osteoporosis on fracture healing in animal studies.
| Osteoporosis | ↓ callus/bone formation 11, 17, 23, 24, 26 ↓ bone mineral content 12, 13, 14, 15, 16, 26 or density 12, 13, 14, 15, 16, 17 ↓biomechanical strength 9, 10, 11, 12, 13, 16, 18, 19, 20, 21, 26 Delay cellular differentiation/processes 9, 12, 13, 15, 16, 18, 21, 24 Radiological delay 12, 16, 18 or no difference 15, 19, 25 |
↑ significant increased, ↓ significant decreased.
