Table 1.
CNT | CMS-R | CMS-V | CMS-V + KET | ANOVA | |
---|---|---|---|---|---|
miR-9-5p | 1 ± 0.22 | 0.94 ± 0.17 | 0.76 ± 0.12* | 1.03 ± 0.24# | F3, 31 = 3,676; p<0.05 |
miR-16-5p | 1 ± 0.20 | 0.83 ± 0.16 | 0.83 ± 0.20 | 0.80 ± 0.08 | F3, 31 = 2,183; p = 0.11 |
miR-29a-5p | 1 ± 0.18 | 0.96 ± 0.21 | 0.98 ± 0.15 | 0.97 ± 0.17 | F3, 33 = 0,066; p = 0.98 |
miR-34a-5p | 1 ± 0.22 | 0.85 ± 0.28 | 0.68 ± 0.18 | 0.77 ± 0.18 | F3, 30 = 2,783; p = 0.06 |
miR-124-5p | 1 ± 0.17 | 0.88 ± 0.11 | 0.81 ± 0.13* | 0.79 ± 0.16* | F3, 30 = 3,669; p<0.05 |
miR-132-5p | 1 ± 0.09 | 0.80 ± 0.13** | 0.85 ± 0.12 | 0.89 ± 0.12 | F3, 29 = 4,241; p<0.01 |
miR-134-5p | 1 ± 0.29 | 0.66 ± 0.07** | 0.79 ± 0.13* | 0.74 ± 0.19* | F3, 30 = 5,153; p<0.01 |
miR-135a-5p | 1 ± 0.12 | 0.77 ± 0.10** | 0.62 ± 0.10*** | 0.76 ± 0.15** | F3, 24 = 10,96; p<0.001 |
miR-137-5p | 1 ± 0.23 | 0.85 ± 0.10 | 0.83 ± 0.11 | 0.80 ± 0.14 | F3, 31 = 2,674; p = 0.06 |
miR-210-5p | 1 ± 0.18 | 0.82 ± 0.08 | 0.79 ± 0.12* | 0.83 ± 0.21 | F3, 32 = 3,218; p<0.05 |
Expression of selected miRNAs in the HPC of rats after CMS and acute ketamine. n = 6–10 (CNT), n = 7–10 (CMS-R), n = 7–10 (CMS-V), n = 7–10 (CMS-V + KET). Newman-Keuls Multiple Comparison Test: *p < 0.05, **p < 0.01, ***p < 0.001 vs CNT; #p < 0.05 vs CMS-V. Data are reported as means ± S.E.M.