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Electron-dense X-ray spectroscopy (EDS) analysis demonstrates iron accumulations within the LV mitochondria of 10 week frataxin KO mice. (A) Scanning transmission electron micrograph of the region subjected to EDS analysis. (B) Corresponding X-ray elemental map for iron Kα (6.4 keV) over the identical field shown in (A). The white arrows in (A) and (B) indicate electron-dense iron accumulations. Scale bar is 1 μm, as indicated.
