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Relation of bursting and dynamic aRME with the gene expression level
(A) Comparison of the expression level of bursty vs. nonbursty genes in EPI and VE cells of the E6.5 stage. ∗∗∗p value <0.001 (Mann–Whitney two-sided U test).
(B) Correlation plot between the mean expression of gene and percent of cells showing monoallelic expression for that gene (r = −0.58 in EPI and −0.61 in VE).
(C) Model representing how transcriptional burst kinetics can lead to dynamic aRME.
