Table 1.
Year 20 Completers (n = 316) | Year 20 Non-completers (n = 153) | P-value for Mean Comparisons | |
---|---|---|---|
Mean (SD) or % | Mean (SD) or % | ||
Demographics | |||
Women | 39% | 45% | .20 |
Age at 6-mo wave (y) | 28.80 (8.99) | 31.95 (9.99) | <.05 |
White | 83% | 70% | .02 |
Diagnostic measures at 6 mo | |||
HiTOP dimensions | |||
SAPS Reality Distortion | 2.77 (5.76) | 3.44 (6.91) | .26 |
SAPS Disorganization | 2.13 (4.01) | 2.16 (3.41) | .95 |
SANS Avolition | 8.74 (7.68) | 10.06 (7.69) | .08 |
SANS Inexpressivity | 6.78 (8.11) | 6.90 (8.21) | .88 |
QLS Global Functioning | 2.70 (1.21) | 2.47 (1.17) | .06 |
DSM-IV Diagnoses | |||
Schizophrenia | 35% | 36% | .91 |
Bipolar disorder with psychotic features | 28% | 25% | .53 |
Major depressive disorder with psychotic features | 18% | 20% | .71 |
Substance-induced psychosis | 7% | 9% | .32 |
Other psychoses | 12% | 10% | .56 |
Outcomes at 20 years | Mean (SD) or % | ||
Psychiatric outcomes | |||
Recovery | 46% | ||
Full Symptom Remission | 29% | ||
Community functioning | |||
Educational attainment (any college) | 40% | ||
Employed | 55% | ||
Public assistance | 63% | ||
Role functioning | 2.55 (1.14) | ||
Living independently over the interval | 0.95 (0.68) | ||
Social functioning | 10.25 (4.49) | ||
WHO-DAS Global Disability | 22.06 (8.70) | ||
Physical health | |||
Diabetes | 21% | ||
Hypertension | 30% | ||
Neural responses | |||
MMN duration (μV) | −1.60 (1.85) | ||
MMN frequency (μV) | −1.75 (1.43) | ||
P3a amplitude (μV) | 8.54 (5.15) | ||
P3a latency (ms) | 390.49 (61.33) | ||
Cognitive functioning | |||
Composite score | −11.55 (73.78) |
Note: SAPS, Scale for the Assessment of Positive Symptoms; SANS, Scale for the Assessment of Negative Symptoms; QLS, Quality of Life Scale; WHO-DAS, World Health Organization Disability Assessment Schedule; MMN, mismatched negativity.