Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Apr 5;47(5):1320–1330. doi: 10.1093/schbul/sbab029

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com

This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

PMC Copyright notice

Fig. 1. — A simplified diagrammatic representation of the kynurenine pathway (KP), experimental design and timeline. (A) The KP of tryptophan catabolism produces kynurenic acid (KYNA) from kynurenine via kynurenine aminotransferases (KATs). (B) Pregnant rat dams were fed control (ECon) or kynurenine laced (EKyn) chow from embryonic day (ED) 15 until ED 22. Sleep recordings and tissue collection for biochemical analyses were carried out in adult male and female offspring after postnatal day (PD) 56.