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. 2021 Jan 22;47(5):1452–1462. doi: 10.1093/schbul/sbaa200

Table 2.

Associations of CNI Subscale and Total Scores With Cerebellar-Cerebral Functional Connectivity in the Main Dataset

MNI Coordinates
Cerebellar Seeds Direction of Association Regions P (FWE-Corr) Cluster Size x y z T
A. Patients with schizophrenia
CNI MC
Crus Iexe1 Positive Inferior frontal gyrus .001 123 56 8 18 5.54
Crus IIexe3 Negative Inferior temporal gyrus .001 126 −44 6 −36 4.47
Lobule VIIImot4 Positive Precuneus <.001 195 −4 −54 34 5.64
CNI SI No significant results
CNI DIS No significant results
CNI total
Crus IIexe3 Negative Inferior temporal gyrus .003 106 −46 8 −40 4.66
Crus IIexe4 Negative Inferior temporal gyrus .003 110 −46 10 −40 5.13
Lobule Vmot2 Positive Precuneus .001 121 −8 −50 38 5.21
B. Healthy controls
CNI MC
Crus Iexe1 Positive Middle occipital gyrus .001 130 −46 −78 28 5.4
Positive Precuneus .001 128 −12 −64 30 4.51
Negative Superior temporal gyrus <.001 339 −62 −2 −2 5.82
Negative Postcentral gyrus .004 101 60 −10 24 5.33
Crus Iexe2 Negative Superior temporal gyrus .0046 98 −64 −8 8 4.7
Lobule VIexe5 Negative Medial superior frontal gyrus .0046 95 10 54 40 5.3
Lobule VIIImot4 Positive Middle occipital gyrus <.001 180 −22 −78 12 4.77
Positive Middle occipital gyrus <.001 129 28 −68 18 4.47
CNI SI
Crus Iexe2 Positive Fusiform gyrus .001 121 −26 −42 −12 5.15
Crus IIexe3 Positive Precuneus .004 100 24 −50 18 5.34
Positive Fusiform gyrus .003 101 −26 −44 −12 5.05
Positive Fusiform gyrus .001 125 30 −44 −14 4.83
Crus IIexe4 Positive Inferior parietal lobule <.001 141 30 −46 40 5.03
Lobule VIexe5 Negative Fusiform gyrus <.001 299 −34 −38 −16 5.49
Negative Fusiform gyrus <.001 139 30 −42 −20 4.98
Lobule VIIImot3 Positive Superior frontal gyrus .002 100 30 60 −2 4.5
CNI DIS
Lobule VIIImot3 Positive Calcarine sulcus <.001 132 −6 −100 −8 5.84
CNI total
Crus Iexe1 Positive Cuneus <.001 304 −20 −58 22 5.77
Positive Middle occipital gyrus .001 118 −44 −74 24 5.25
Negative Middle occipital gyrus .002 109 38 −86 8 5.11
Negative Superior temporal gyrus <.001 170 −60 4 4 4.55

Note: CNI, the abridged version of the Cambridge Neurological Inventory; MC, motor coordination subscale; SI, sensory integration subscale; DIS, disinhibition subscale. The brain regions in bold were validated in the replication dataset. The threshold was voxel-level P < .001 and cluster-level FWE correction P < .005.