Table 5. Multivariable Logistic Regression: Association of Age With Treatmentsa.
| Treatment | OR (95% CI) | P value |
|---|---|---|
| Chemotherapy vs none | ||
| 18-39 y (n = 1243) | 1 [Reference] | NA |
| 40-64 y (n = 3828) | 0.52 (0.45-0.60) | .001 |
| ≥65 y (n = 3630) | 0.16 (0.12-0.20) | .001 |
| LSS vs amputation | ||
| 18-39 y (n = 521) | 1 [Reference] | NA |
| 40-64 y (n = 1218) | 1.20 (0.90-1.60) | .21 |
| ≥65 y (n = 1367) | 1.49 (1.00-2.23) | .05 |
| Preoperative vs postoperative RT | ||
| 18-39 y (n = 759) | 1 [Reference] | NA |
| 40-64 y (n = 2710) | 1.12 (0.92-1.35) | .26 |
| ≥65 (n = 2368) | 0.90 (0.69-1.17) | .44 |
Abbreviations: LSS, limb sparing surgery; OR, odds ratio; RT, radiation therapy.
a
The following variables were included for adjustment: sex, race/ethnicity, insurance status, median income of patient’s zip code, education level in patient’s zip code, living location, distance to hospital, comorbidities, transition in care, primary site, grade, tumor size, tumor stage, depth of extension, and surgical margin.