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. 2021 Aug 16;14:4485–4497. doi: 10.2147/OTT.S324641

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© 2021 Song et al.

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Strategy for quantifying TILs in endometrioid EC. (A) Representative H&E staining of endometrioid EC to define the tumor center and periphery. (B and C) Quantification of CD3+ cells (B) and CD8+ cells (C) in the tumor center and periphery. Red box, hotspot (single 1-mm² box); green boxes, tumor periphery (five 1-mm² boxes); yellow boxes, central areas (five 1-mm² boxes). Scale bars: 1 mm.

Abbreviation: H&E, hematoxylin and eosin.