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Neoantigen load and PD-L1 expression level in MSI-H and MSS EC. (A) TMB per megabase in tumor DNA exons and introns detected by ColoSeq. Blue and green represent MSI-H and MSS tumors, respectively. (B–D) Average numbers of PD-L1–expressing tumor cells and TILs (B), CD3+ immune cells (C), and CD8+ immune cells (D) identified by IHC. NS, nonsignificant at p>0.05, *p<0.05, **p<0.01 (Mann–Whitney U-test).
Abbreviation: HPF, high-power field.
