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. 2021 Aug 16;14:1045–1063. doi: 10.2147/JAA.S318892

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© 2021 Corren et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

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Study information. (A) CONSORT diagram of patient disposition and (B) study design. *NAC occurred at Week 17, after 16 weeks of treatment. ^†SCIT dosing regimen is detailed in Supplementary Table 1 in this article’s Online Repository at https://www.dovepress.com/.

Abbreviations: BAU, bioequivalent allergy unit; FAS, full analysis set; NAC, nasal allergen challenge; PNIF, peak nasal inspiratory flow; PPS, per protocol set; q2w, every 2 weeks; R, randomization; SAF, safety analysis set; SC, subcutaneous; SCIT, subcutaneous immunotherapy; SPT, skin prick test; TG, timothy grass; TNSS, total nasal symptom score.